The chloride shift is

  1. movement of Cl⁻ out of red cells
  2. binding of Cl⁻ to haemoglobin
  3. movement of Cl⁻ into red cells as HCO₃⁻ moves out, maintaining charge balance
  4. movement of O₂ into plasma
Answer

C) movement of Cl⁻ into red cells as HCO₃⁻ moves out, maintaining charge balance

Electrical neutrality is maintained. AS & A Level Biology · Topic 8 Transport in Mammals · 8.2 Transport of oxygen and carbon dioxide

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