The induced-fit hypothesis states that

  1. the active site changes shape slightly when the substrate binds
  2. enzymes act on many substrates
  3. the substrate changes the enzyme permanently
  4. the active site is rigid
Answer

A) the active site changes shape slightly when the substrate binds

The active site moulds around the substrate. AS & A Level Biology · Topic 3 Enzymes · 3.1 Mode of action of enzymes

Biology MCQ · More A Level Biology: Enzymes MCQs · Practise