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A Level Biology: Genetic technology MCQs — Biology (page 2)

33 multiple-choice questions on A Level Biology: Genetic technology from Biology, each with the correct answer and, where available, a teacher's explanation. Read through them to revise the chapter, then practise the same questions one by one to test yourself.

26. Bt toxin genes come from

  1. the bacterium Bacillus thuringiensis
  2. soybean
  3. Chinook salmon
  4. jellyfish

Answer: A) the bacterium Bacillus thuringiensis

Explanation: Bt = Bacillus thuringiensis. AS & A Level Biology · Topic 19 Genetic Technology · 19.3 Genetically modified organisms in agriculture

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27. Recombinant factor VIII is safer than factor VIII from donated blood because

  1. it cures haemophilia permanently
  2. there is no risk of contamination with viruses such as HIV
  3. it is a carbohydrate
  4. it is from pigs

Answer: B) there is no risk of contamination with viruses such as HIV

Explanation: Blood products carried infection risks. AS & A Level Biology · Topic 19 Genetic Technology · 19.2 Genetic technology applied to medicine

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28. In gene therapy for SCID, the functional gene is inserted into

  1. the patient's T-lymphocytes or bone marrow stem cells using a viral vector
  2. gametes
  3. red blood cells
  4. liver cells only

Answer: A) the patient's T-lymphocytes or bone marrow stem cells using a viral vector

Explanation: Ex vivo treatment of immune cells. AS & A Level Biology · Topic 19 Genetic Technology · 19.2 Genetic technology applied to medicine

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29. In gel electrophoresis, which fragments travel furthest?

  1. Fragments with most adenine
  2. The longest fragments
  3. The shortest fragments
  4. Uncharged fragments

Answer: C) The shortest fragments

Explanation: Small fragments move faster through the gel. AS & A Level Biology · Topic 19 Genetic Technology · 19.1 Principles of genetic technology

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30. An advantage of recombinant human insulin over pig insulin is that it

  1. is cheaper to extract from pancreases
  2. lasts forever
  3. is identical to human insulin, causing fewer immune reactions
  4. is made in pigs

Answer: C) is identical to human insulin, causing fewer immune reactions

Explanation: Identical structure reduces reactions. AS & A Level Biology · Topic 19 Genetic Technology · 19.2 Genetic technology applied to medicine

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31. In PCR, the temperature of about 95 °C is used to

  1. separate the DNA strands
  2. bind primers
  3. activate ligase
  4. extend new strands

Answer: A) separate the DNA strands

Explanation: Denaturation breaks H-bonds. AS & A Level Biology · Topic 19 Genetic Technology · 19.1 Principles of genetic technology

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32. DNA ligase

  1. joins the sugar–phosphate backbones of DNA fragments
  2. makes primers
  3. cuts DNA
  4. separates DNA strands

Answer: A) joins the sugar–phosphate backbones of DNA fragments

Explanation: Ligase seals phosphodiester bonds. AS & A Level Biology · Topic 19 Genetic Technology · 19.1 Principles of genetic technology

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33. An ethical concern about genetic screening is that

  1. insurance companies or employers might discriminate
  2. it is always 100% accurate
  3. it cures disease
  4. it is too cheap

Answer: A) insurance companies or employers might discriminate

Explanation: Confidentiality concerns. AS & A Level Biology · Topic 19 Genetic Technology · 19.2 Genetic technology applied to medicine

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