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A Level Biology: Homeostasis MCQs — Biology

27 multiple-choice questions on A Level Biology: Homeostasis from Biology, each with the correct answer and, where available, a teacher's explanation. Read through them to revise the chapter, then practise the same questions one by one to test yourself.

1. Insulin lowers blood glucose by

  1. increasing glucose uptake by cells and glycogen synthesis
  2. stimulating gluconeogenesis
  3. stimulating glycogen breakdown
  4. reducing glucose transporters

Answer: A) increasing glucose uptake by cells and glycogen synthesis

Explanation: Insulin acts on liver and muscle. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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2. Which substance is normally absent from the glomerular filtrate?

  1. Plasma proteins
  2. Sodium ions
  3. Urea
  4. Glucose

Answer: A) Plasma proteins

Explanation: Proteins are too large. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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3. ABA causes stomata to close in water stress by

  1. causing K⁺ to leave guard cells so water follows
  2. increasing photosynthesis
  3. pumping water into guard cells
  4. causing K⁺ to enter guard cells

Answer: A) causing K⁺ to leave guard cells so water follows

Explanation: Guard cells lose water. AS & A Level Biology · Topic 14 Homeostasis · 14.2 Homeostasis in plants

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4. The inner wall of a guard cell is

  1. thinner than the outer wall
  2. thicker and less elastic than the outer wall
  3. absent
  4. made of suberin

Answer: B) thicker and less elastic than the outer wall

Explanation: Uneven thickening causes curving. AS & A Level Biology · Topic 14 Homeostasis · 14.2 Homeostasis in plants

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5. Urea is produced in the liver by

  1. ultrafiltration
  2. hydrolysis of fats
  3. breakdown of glucose
  4. deamination of excess amino acids

Answer: D) deamination of excess amino acids

Explanation: Amino groups → ammonia → urea. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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6. Which component of the cascade does glucagon binding activate first?

  1. A G-protein
  2. cAMP
  3. Protein kinase A
  4. Glycogen phosphorylase

Answer: A) A G-protein

Explanation: Receptor → G-protein → adenylyl cyclase. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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7. Homeostasis is best described as

  1. maintaining a constant internal environment
  2. making hormones
  3. producing urine
  4. responding to external stimuli only

Answer: A) maintaining a constant internal environment

Explanation: Definition. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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8. In negative feedback,

  1. a change triggers a response that reverses the change
  2. a change is amplified
  3. there is no set point
  4. only hormones are involved

Answer: A) a change triggers a response that reverses the change

Explanation: Returns to the set point. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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9. Glucose test strips contain

  1. amylase and maltase
  2. insulin and glucagon
  3. ADH and aquaporins
  4. glucose oxidase and peroxidase

Answer: D) glucose oxidase and peroxidase

Explanation: The two enzymes produce a colour. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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10. In water stress, ABA is produced by

  1. flowers
  2. guard cells only
  3. xylem vessels
  4. roots and leaves

Answer: D) roots and leaves

Explanation: ABA is a stress hormone. AS & A Level Biology · Topic 14 Homeostasis · 14.2 Homeostasis in plants

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11. Glucose is reabsorbed from the PCT by

  1. cotransport with sodium ions
  2. simple diffusion only
  3. endocytosis
  4. osmosis

Answer: A) cotransport with sodium ions

Explanation: Na⁺-glucose cotransporters. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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12. In the cell signalling cascade for glucagon, the second messenger is

  1. cyclic AMP
  2. glycogen
  3. adenylyl cyclase
  4. G-protein

Answer: A) cyclic AMP

Explanation: cAMP. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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13. Stomata open when guard cells

  1. produce ABA
  2. become flaccid
  3. take up K⁺ ions and water, becoming turgid
  4. lose K⁺ ions and water

Answer: C) take up K⁺ ions and water, becoming turgid

Explanation: Turgid guard cells curve apart. AS & A Level Biology · Topic 14 Homeostasis · 14.2 Homeostasis in plants

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14. ADH is released from the

  1. pancreas
  2. hypothalamus directly into urine
  3. anterior pituitary
  4. posterior pituitary

Answer: D) posterior pituitary

Explanation: Made in hypothalamus, released from posterior pituitary. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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15. Stomata must open to

  1. let oxygen in for respiration only
  2. let carbon dioxide in for photosynthesis
  3. absorb light
  4. stop transpiration

Answer: B) let carbon dioxide in for photosynthesis

Explanation: The trade-off is CO₂ gain vs water loss. AS & A Level Biology · Topic 14 Homeostasis · 14.2 Homeostasis in plants

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16. Proton pumps in guard cell membranes

  1. make ABA
  2. pump water in
  3. pump H⁺ out, leading to K⁺ entry
  4. pump K⁺ out

Answer: C) pump H⁺ out, leading to K⁺ entry

Explanation: The membrane becomes hyperpolarised. AS & A Level Biology · Topic 14 Homeostasis · 14.2 Homeostasis in plants

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17. Which layer of the glomerulus/Bowman's capsule acts as the main filter?

  1. Proximal convoluted tubule
  2. Podocytes
  3. Basement membrane
  4. Endothelium

Answer: C) Basement membrane

Explanation: The basement membrane stops proteins. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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18. In ABA signalling, the second messenger is

  1. calcium ions
  2. cyclic AMP
  3. water
  4. potassium ions

Answer: A) calcium ions

Explanation: Ca²⁺ acts as a second messenger. AS & A Level Biology · Topic 14 Homeostasis · 14.2 Homeostasis in plants

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19. Podocytes have

  1. aquaporins
  2. filtration slits between their foot processes
  3. cilia
  4. microvilli

Answer: B) filtration slits between their foot processes

Explanation: Slits allow filtrate through. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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20. ADH increases water reabsorption by

  1. closing aquaporins
  2. increasing glomerular pressure
  3. pumping water actively
  4. causing aquaporins to be inserted into collecting duct membranes

Answer: D) causing aquaporins to be inserted into collecting duct membranes

Explanation: More water channels. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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21. Osmoreceptors that detect blood water potential are in the

  1. adrenal gland
  2. posterior pituitary
  3. hypothalamus
  4. kidney

Answer: C) hypothalamus

Explanation: Hypothalamus contains osmoreceptors. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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22. The enzyme cascade in liver cells amplifies the signal because

  1. cAMP is a hormone
  2. receptors are destroyed
  3. glucagon is used up
  4. each activated enzyme activates many molecules of the next enzyme

Answer: D) each activated enzyme activates many molecules of the next enzyme

Explanation: Amplification by phosphorylation. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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23. Stomata opening in the morning even in constant light shows

  1. a response to ABA
  2. a daily (circadian) rhythm
  3. wilting
  4. plasmolysis

Answer: B) a daily (circadian) rhythm

Explanation: Internal clock control. AS & A Level Biology · Topic 14 Homeostasis · 14.2 Homeostasis in plants

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24. Glucagon is secreted by

  1. α cells of the islets of Langerhans
  2. the adrenal medulla
  3. the liver
  4. β cells

Answer: A) α cells of the islets of Langerhans

Explanation: α cells make glucagon. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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25. The renal pelvis

  1. contains the loops of Henle
  2. filters blood
  3. collects urine and leads into the ureter
  4. makes ADH

Answer: C) collects urine and leads into the ureter

Explanation: Pelvis drains into ureter. AS & A Level Biology · Topic 14 Homeostasis · 14.1 Homeostasis in mammals

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